Ethyl 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylate - Names and Identifiers
Ethyl 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylate - Physico-chemical Properties
Molecular Formula | C11H9BrClN3O2
|
Molar Mass | 330.57 |
Density | 1.67±0.1 g/cm3(Predicted) |
Melting Point | 117-118 °C |
Boling Point | 421.3±45.0 °C(Predicted) |
pKa | -2.48±0.29(Predicted) |
Ethyl 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylate - Introduction
ETHYL 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-is an organic compound with the chemical formula C12H9BrClN3O2. It is a solid with white to yellowish crystals. The following is a detailed description of the nature, use, preparation and safety information of K acid:
Nature:
K acid is a photosensitive compound whose structure contains bromine and chlorine atoms, as well as pyrazole, pyridine and ethyl formate groups. It is stable at room temperature, but will decompose under strong light. It can be dissolved in some organic solvents, such as methanol and dichloromethane.
Use:
K acid is widely used as a synthetic intermediate in chemical research. It can be used in organic synthesis reactions such as ring-closing reactions and catalytic reactions. In addition, K acid can also be used as a precursor for antibacterial agents and insecticides.
Preparation Method:
K acid can be synthesized by the following steps:
1. reacting pyrazole with acid chloride in a matrix to obtain acid chloride derivatives;
2. reacting the acid chloride derivative with 3-chloropyridine to generate the precursor of K acid;
3. Finally, K acid is obtained by reaction with a bromine compound.
Safety Information:
K acid in the correct use and storage conditions, the human body and the environment is relatively safe. But because it is a light-sensitive compound, it can decompose under light conditions, releasing harmful gases or producing dangerous reactions. Therefore, when using K acid, necessary protective measures should be taken to avoid prolonged exposure to the sun. At the same time, for the storage and handling of K acid, the corresponding chemical safety regulations need to be observed. During use, appropriate protective equipment, such as gloves and goggles, should be used to avoid direct contact and inhalation of particles or gases. In all cases, the relevant safety data sheets should be carefully read and observed.
Last Update:2024-04-10 22:29:15